There is a lot of excitement these days about science, technology, and innovation and the potential for these activities to contribute to economic and social development globally. The flurry of activity begs the question, how much of this excitement is supported by scientific facts? To help answer this question, the US Global Development Lab at USAID commissioned a project to create and populate a map of the evidence base for science, technology, innovation, and partnerships (STIP). As part of the project, scoping research was conducted to identify not just where there are evidence clusters and gaps, but also where the demand for new evidence by stakeholders is the greatest. In the recently published scoping paper, I and my co-authors analyze the data in the map together with the information from the stakeholders to recommend priorities for investment in new research on STIP. While there is good evidence out there, new research is necessary for strategies and programming to fully benefit from scientific facts. In this post, I briefly describe the research we conducted, summarize a few of the many findings, and list some of our recommendations.